X-Therma Inc. Production Chemist Richmond, CA · Full time

Production Chemist

Description

X-Therma, a venture backed biotech company pioneers ground-breaking cold chain technology via a convergent biopreservation platform, to advance Regenerative Medicine and make available safe and on-demand organs, engineered tissues, and cell & gene therapies to patients in need with a total addressable market of over $10B. X-Therma collaborates with renowned research institutions such as Lawrence Berkeley National Laboratory and Johns Hopkins University and is supported with significant funding from the US Department of Defense, National Science Foundation, California Institute of Regenerative Medicine, etc.


X-Therma has made a quantum leap in demonstrating significant extension of organ shelf-life from a few hours to a few days in collaboration with a World leading surgical team. This is a paradigm shift that could make worldwide organ sharing possible and eliminate organ discard. We are generating revenue in the Cell & Gene Therapy (CGT) field and are currently experiencing exponential growth of commercial partnerships with the top CGT developers. Immediately, the technology could resolve current bottlenecks in Regenerative Medicine biomanufacturing and processing (TAM $8.8B) and allow “off-the-shelf" living medicines in this hyper-growth space.

Recently, our technology was designated as a Breakthrough Device by the FDA.

Joining Team Excellence:

With respect for life, we have a bold vision to create something great that has never been done before: We are wary of what could go wrong, but obsessed with what can go right. We are mission-driven, intellectually honest and relentless learners, ambitious, courageous, and extraordinarily persistent. “Giving up” does not exist in our vocabulary. We respect and support each other to get better every day and make the world a better place. We are in the San Francisco East Bay near Berkeley, not only known for its beautiful scenery and comfortable weather all year round, but also you can truly embrace the breath of innovations and dream building spirit of San Francisco’s Biobay.

Check out the team you will work with:

https://www.linkedin.com/feed/update/urn:li:activity:6863381188938203136/

What’s in it for you?

You will have a great opportunity to contribute to groundbreaking, life-saving products. You will be part of a team producing our novel life-saving molecules by performing synthesis, purification and process optimization within a small and supportive team environment. This role demands a highly goal-driven approach and the ability to focus on time-sensitive objectives within the most urgent priorities.

What you will do:

You will have experience and desire to:

  • Jump into a small team environment for production of life-saving molecules
  • Perform large scale purification of small molecules, peptides and similar molecules
  • Assist in synthesis research and development of new molecules during scale-up
  • Maintain a clean laboratory space and production equipment according to cGMP (current Good Manufacturing Practice) regulatory standards
  • Maintain detailed records of results which may include collecting, extracting and entering data via both electronic and paper files (i.e., notebooks, logbooks, batch records, etc.) for regulatory submissions
  • Analyze and troubleshoot methods and data obtained from individual projects
  • Recommend alternatives and suggestions to improve processes, validity and/or accuracy
  • Maintain and troubleshoot instruments, equipment and general lab or production areas
  • Deliver results through the application of chemistry skills, systematic problem-solving and validation of performance in collaboration with all stakeholders.
  • Participate in the development of new processing methods
  • Help quote and procure needed laboratory instrumentation

Qualification:

The following qualifications will help an individual excel in this role:

  • B.S./M.S. degree in chemistry or related field
  • 1-2 years of relevant work experience
  • Skillset in process development: organic synthesis, purification, characterization
  • Prior responsibility for working from technical SOPs, Batch Production Records (BPR) and technical reports
  • Ability to adapt and respond quickly to change in a dynamic, high-growth environment and radiate a positive impact to the team.
  • Thrive in an early stage environment with a proactive attitude; no task is too big or too small for you
  • A strong work ethic and self-motivation to deliver results within timeline
  • Strong analytical and problem-solving skills, organization, and attention to details
  • Must be able to work in a laboratory and office setting without prohibitive limitations.
  • Able to physically lift up to 50 lbs and assist with moving/installing laboratory equipment


Position is eligible for option awards and benefits including medical, dental and vision insurance, 401(k) participation, vacation, and paid holidays.

On-site position.

Our package includes:

• Competitive base salary

• Health, vision, and dental benefits, with high family coverage

• 401(k) savings plan

• Employee Stock Option Plan

• 5-Day marriage leave policy

• Safe work environment for COVID response and high-quality PPEs.

• And more!

X-Therma is an Equal Opportunity Employer. X-Therma does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, non-disqualifying physical or mental disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need.