VitriVax Inc. Senior Scientist, Analytical R&D: mRNA-LNP Vaccines Boulder, CO · Full time

VitriVax, Inc. is creating thermostable, single-injection vaccines using an innovative technology platform called ALTA™. Fundamentally, ALTA™ products are formulations of antigens, adjuvants or nucleic acids that use an innovative manufacturing process combining particle engineering technologies from the pharmaceutical and semiconductor industries. Thermostable, single-injection products will revolutionize the vaccine industry and have attracted significant industry, government, and philanthropic interest. Learn more about VitriVax by visiting our website at If you are interested in joining VitriVax, Inc. we are always looking for talented individuals. Below is one opportunity to help make vaccines accessible to everyone. See all opportunities at VitriVax, Inc: HERE The Senior Scientist in analytical research and development in the Product Research and Development (PRD) group is responsible for developing and applying analytical methods to characterize ALTA™ products and in-process materials which contain nucleic acids and/or lipids. The senior scientist must adapt and routinely apply chromatographic, spectroscopic, molecular, and biological methods to ALTA™ products which contain dilute antigens and insoluble ALD coatings. This role reports to the Head of PRD and will work with a team of scientists and research associates for training and study execution. This is a full-time position, located in Boulder, Colorado.


Responsibilities and Duties:

  • In-house resource for nucleic acid and lipid-based analytical method development
  • Designs, authors, and executes protocols to develop and qualify analytical methods.
  • Independently plans and executes studies to investigate ALTA™ product stability, process yield and composition.
  • Prepares study reports and presents data to teams, partners and executives.
  • Helps train Product Research and Development staff to address project needs.
  • Works effectively and dynamically in cross-functional teams to complete partner projects
  • Maintains equipment and ensures that methods and equipment are fit-for-purpose.
  • Supports Quality Control testing for product release and stability testing.
  • Works closely with Formulation Development and Quality Assurance to establish specifications.
  • Contributes toward portions of IND or BLA eCTD module 2 and 3.  
  • Adheres to Company policies and safety guidelines 

Education and Experience

  • Must be able to perform the responsibilities and duties listed above.
  • A PhD degree in Analytical Chemistry, Biochemistry, with dissertation research characterizing nucleic acids, lipids, and/or biological materials.
  • Analytical training including advanced characterization of nanoparticles, lipids and nucleic acids using molecular (PCR), spectroscopic, calorimetric and chromatographic tools is required.
  • Hands on experience designing and characterizing LNP-mRNA preferred.
  • Experience with analytical methods for protein characterization and lyophilization preferred.
  • Supervisory experience and cross functional team leadership.
  • Understanding of ICH Q8, Q9, and Q10 and Quality by Design.
  • Proficient in the use of statistical analysis methods and standard office tools like Excel and Word.

Core Skills and Competencies

All VitriVax employees are expected to share the following values.


We are team players who say what we do and do what we say. We respect our obligations and are transparent in our communication. We present all data factually. When presented with ambiguous situations, we strive to do the right thing


We create value by developing superior products and processes. We have a curious mindset, apply an analytical approach and take calculated risks. We take on difficult problems and break barriers.


We are passionate about making vaccines accessible to everyone. We share our enthusiasm with purpose.  We are never satisfied with the status quo and want to make a difference.


We seek quality information, decisions and people. We put safety first and approach every opportunity with a right first-time mindset that is focused on the end goal. We are committed to continuous improvement and elimination of waste.

Salary and Benefits

The position may be filled at the Senior Scientist or Scientist level. The level will be determined by the applicant’s experience and alignment with current and future responsibilities.

·      Senior Scientist: PhD+5 years or BA+10 years in an academic program aligned with VitriVax needs – range $130,000 - $170,000 DOE

·      Scientist – PhD or BA+5 years in an academic program aligned with VitriVax needs – range $100,000 - $120,000 DOE

All full-time employees are eligible for the following benefits.

·      Stock Options

·      401(k) with generous Company match

·      Flexible work schedule

·      Generous PTO

·      Health, Dental and Vision insurance

·      Short Term Disability insurance and Voluntary AD&D Insurance


VitriVax, Inc., is an Equal Opportunity Employer and does not discriminate based on race, color, gender, sexual orientation, gender identity or expression, religion, disability, national origin, protected veteran status, age, or any other status protected by applicable national, federal, state, or local law.

VitriVax, Inc., requires all staff to be vaccinated against communicable diseases as recommended by the CDC prior to employment.


$100,000 - $170,000 per year