NeuroDex, Inc Senior Scientist Natick, MA · Full time

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NeuroDex is a dynamic, fast-growing biotechnology company developing blood tests for neurological diseases, with a special focus on neurodegeneration and psychiatry and primary expertise is in the biology, function, and composition of plasma extracellular vesicles. Our tests are based on ExoSORT, a unique integrated platform developed by NeuroDex for isolation and fine analysis of nano-sized extracellular vesicles released by the brain into the blood plasma.

We are seeking a highly motivated, detail-oriented Senior Scientist to join our growing team. This is a full-time position, with immediate goal of optimization and implementation of our novel immunoaffinity platform for exosome capture and analysis, to be used in biomarker discovery. The downstream analyses include protein, RNA, and lipid profiling through direct measurement and omics approaches. Senior Scientist will be responsible for the development of NeuroDex proprietary diagnostic assays and biomarker signatures and involved in collaborative studies with pharma and/or biotech, including clinical trials. The position involves both benchwork and strategic thinking. Senior scientist will instruct one or more Associate Scientists and report directly to the Chief Scientific Officer of NeuroDex.  

Key Responsibilities:

• Design and execution of well-controlled experiments to demonstrate assay feasibility
• Assay development, optimization, and troubleshooting
• Assay validation
• Working with large collections of clinical specimens to generate proof of concept data
• Systematic and organized data collection, presentation, interpretation, and reporting 
• Keeping abreast with the latest advances in the field (biomarkers, extracellular vesicles, neurodegenerative disease)
• Training, and supervision of Associate Scientist(s)
• Communication and oversight of work by contract research organizations (CROs).
• Coordination of collaborative projects

Required Qualifications:

• PhD or equivalent degree in a relevant field with 2+ years of laboratory research experience (academia or industry)
• Familiarity with key methods and laboratory techniques in biochemistry and molecular biology
• Experience in handling clinical specimens, biofluids or tissues.
• Familiarity with medium- and high-throughput immunoassays, (ELISA, Luminex, Mesoscale, etc.)
• Knowledge of diagnostic assays and biomarker development
• Critical and independent thinking
• Excellent oral and written communication skills, ability to present data and progress reports
• Leadership potential and organizational skills

Preferred Qualifications:

• Working knowledge of extracellular vesicles
• Familiarity with nucleic acid isolation, qPCR, and RNAseq.
• Experience in proteomic and/or lipidomic analyses
• Experience in grant/manuscript writing or startup environment
• Goal-oriented team management
• Experience operating in a highly regulated (CLIA, FDA) environment

At NeuroDex, we encourage transparency, collegiality, and on-job training, our scientists have every opportunity for career development and involvement in the company strategy. Our work environment is friendly, collegial, and informal.

NeuroDex is an Equal Opportunity Employer offering a competitive salary and benefits package. Applicants should be legally entitled to work for any employer in the US. Our offices and laboratory are located in Natick, Massachusetts.