Join Our Growing Team Senior Scientist, Process Development (Hybrid) Watertown, MA · Full time

At Corner Therapeutics, Inc., our mission is to transform standard of care, ushering in a new era of robust, rapid, patient-friendly and low-cost immunotherapies – even for the most difficult to treat diseases. Our versatile dendritic cell hyperactivation (hDC) platform is unique in its ability to address a virtually unbounded range of cancers and infectious diseases which induces exceptional memory T cell responses that provide robust and durable immunity. Our dynamic workplace has tremendous opportunity for growth, and we are seeking talented individuals that are inspired and motivated to make exponential strides in curing disease through immunotherapy treatments.

Description

The Role:

The position of Senior Scientist, Process Development will play a critical role in the development of Corner Therapeutic’s novel classes of immune modulating therapies and the conduct of clinical trials. He or she will report to the Chief Technology Officer and be an integral leader of the Research and Development team. They will be tasked with overseeing the transition from early development of our lead candidates across all therapeutic areas to prepare for first-in-human trials. A key portion of this role will include participating in the development of comprehensive drug product formulation and method strategies for clinical manufacturing. In addition, this role will be supporting and managing technology transfer to external CDMOs and provide high quality materials for key internal IND enabling studies. This role will have an excellent opportunity for future growth and career development as the team and company grow. This position is a laboratory position at our facility in Watertown, MA some remote work available.

 

The Responsibilities:

  • Work with internal, cross-functional teams to develop and optimize process and formulation methods to support move from proof of concept to clinical stage development
  • Optimize and formulate drug product methods for use in in vitro and in vivo studies
  • Design and perform routine studies to characterize formulations and oversee initial stability studies
  • Manage and provide technical guidance for technology transfers to external CDMOs
  • Maintain thorough and detailed electronic lab notebooks and documentation records
  • Write and review Research Operation Protocols to enable technology transfer
  • Review protocols and reports from external partners
  • Provide content for regulatory filings as an SME
  • Analyze, interpret, and present key results at group and project team meetings to internal and external stakeholders
  • Adhere to all laboratory safety requirements and procedures
  • Assist in maintaining general laboratory functionality, including lab equipment maintenance and the ordering and receiving of lab supplies


Preferred Qualifications:

  • PhD in a biological science, immunology or equivalent, with 3+ years relevant industry experience
  • Experience with process development and drug product clinical life cycle of biologics, cell therapies, or other CBER products preferred
  • Prior experience with management of CDMOs preferred
  • Prior experience and a track record of working on project teams toward successful drug milestones (INDs, BLAs, etc)
  • Experience with LNP or lipid formulations a plus
  • Excellent written and oral communication skills and project management experience


The Culture:

We at Corner Therapeutics seek to attract individuals who believe in delivering exponential hope and impact for patients living with devastating disease.


Guided by a shared love of learning and aspirations for scientific excellence, we hold a common belief that work communities should be a place of diverse ideas, mindful focus and authentic fun. We take a shared ownership approach towards building and amazing people and patient-centric culture.


Game-changing science and bold business scaling can only be achieved when passionate people commit collaboratively to an extraordinary vision and to each other. We hope you will join us!


Let’s build something bold, TOGETHER.

 

The Benefits:

Corner Therapeutics also seeks to build a robust total rewards and benefits package that supports the physical, mental and financial wellness of every team member with:

  • Medical, Dental, Vision and company-supplemented Health Savings Account (HSA)
  • 4 weeks’ vacation (with roll-over available), 5 sick days and 12 paid holidays 
  • 401K with company match
  • Long- and short-term disability, Life insurance.
  • Amazing colleagues in a dynamic start-up environment
  • A new biotech building with FREE parking near Watertown’s vibrant Arsenal Yards!

 

Corner Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.