Hesperos, Inc. iPSC Biologist - Scientist I/II Orlando, FL · Full time

Apply for iPSC Biologist - Scientist I/II

About You 

• You are a rigorous experimentalist who takes pride in your ability to execute at the bench.
• You are conscientious and pay almost obsessive attention to detail, as organized documentation is second nature. 
• You are curious, love learning, and are eager to take on hard problems. 
• You thrive in a fast-paced environment and enjoy pushing the edge of what is possible.
• You are resourceful and like to work independently but are not shy to ask for advice. 

What You’ll Do 

• Keep detailed and organized records of experimental protocols and results 
• Design, optimize and oversee day-to-day experiments 
• Present findings and data analysis in research meetings. 
• Compile and interpret data and prepare presentations for management review 
• Assign tasks to and mentor junior scientists (research associates and research assistants) 
• Manage multiple projects (2-4) simultaneously ensuring each project meets required deliverables in an appropriate deadline 
• Develop a statement of work (SOW) and standard operating procedures (SOPs) for client contracts
• Present data in client meetings 
• Establish and oversee quality control in all aspects of your team projects 
• Write and submit final reports and manuscripts under the guidance of a Senior Scientist at the conclusion of a project
• Create, maintain, and curate human patient-derived cell sample biorepository, associated QC materials/reagents, and protocols for use/application
• Contribute to the establishment of protocols for directed differentiation of human pluripotent cells to model a variety of cell types and diseases.
• Support the development of disease phenotype-specific molecular and functional assays in relevant cell types differentiated from human pluripotent stem cells (such as enzymatic activity, receptor function, and metabolic assays).  

Basic Qualifications 

• Minimum Requirements: Master's with 3+ years or Ph.D. with 0+ years of experience. 
• Proficiency in common office software (typically Microsoft Word, Excel, and PowerPoint)
• Ability to lead and mentor research associates 
• Experience with mammalian cell culture 
• Creativity and the ability to work with an interdisciplinary team to achieve technical and corporate milestones
• Exceptional communication, critical thinking, and problem-solving skills 
• Knowledge of human pluripotent stem cell culture, characterization, and QC.
• Experience with ESC/iPSC differentiation protocols, reprogramming techniques, and functional readouts.
• Working knowledge of in vivo application of iPSC-derived cell models
• Direct hands-on experience with a variety of cell-based and molecular biology readout technologies, such as flow cytometry immunophenotyping and analysis, FACS (cell sorting), qPCR, ELISA, and high-content and confocal imaging.
• Ability to work on weekends when necessary.

Preferred Qualifications 

Prior experience in: 

• Managing junior technicians and/or graduate or undergraduate researchers 
• Experience with Monday.com, Instagantt, and Python 
• Independent planning and execution of complex in vitro experiments 
• Experience with co-culture models or 3D culture systems, MPS (micro physiological system) (3D multi-cellular culture models, organoids, bioprinting, organ-on-a-chip) is a plus.
• Working knowledge of genome editing tools (CRISPR-Cas9, base editing, prime editing) is a plus