Searching for an experienced, new team member to share their knowledge + love of research to further the mission of Hesperos, Inc.
Description
About You
You are a rigorous experimentalist who takes pride in your ability to execute at the bench.
You are conscientious and pay almost obsessive attention to detail, as organized documentation is second nature.
You are curious, love learning, and are eager to take on hard problems.
You thrive in a fast-paced environment and enjoy pushing the edge of what is possible.
You are resourceful and like to work independently but are not shy to ask for advice.
What You’ll Do
Keep detailed and organized records of experimental protocols and results
Design, optimize and oversee day-to-day experiments
Present findings and data analysis in research meetings.
Compile and interpret data and prepare presentations for management review
Assign tasks to and mentor junior scientists (research associates and research assistants)
Manage multiple projects (2-4) simultaneously ensuring each project meets required deliverables by an appropriate deadline
Develop a statement of work (SOW) and standard operating procedures (SOPs) for client contracts
Present data in client meetings
Establish and oversee quality control in all aspects of your team projects
Write and submit final reports and manuscripts under the guidance of a Senior Scientist at the conclusion of a project
Develop models of barrier tissues (BBB, Kidney, GI tract)
Measure efflux/influx transporter activity, tight junction formation, TEER, and transport kinetics
Basic Qualifications
Minimum Requirements: Master's with 3+ years or Ph.D. with 0+ years of experience.
Proficiency in common office software (typically Microsoft Word, Excel, and PowerPoint)
Ability to lead and mentor research associates
Experience with mammalian cell culture
Creativity and the ability to work with an interdisciplinary team to achieve technical and corporate milestones
Exceptional communication, critical thinking, and problem-solving skills
Knowledge in culturing brain microvascular endothelial cells, astrocytes, pericytes, and models of the BBB
Experience with TEER measurement methodologies
Experience in transporter activity studies and modulation of transporter activity
Ability to work on weekends when necessary.
Preferred Qualifications
Prior experience in:
Managing junior technicians and/or graduate or undergraduate researchers
Experience with Monday.com, Instagantt, and Python
Independent planning and execution of complex in vitro experiments
Experience with co-culture models or 3D culture systems, MPS (micro physiological system) (3D multi-cellular culture models, organoids, bioprinting, organ-on-a-chip) is a plus.
Working knowledge of genome editing tools (CRISPR-Cas9, base editing, prime editing) is a plus
Additional experience in glomerular and proximal tubule biology